Blocking nitric oxide, a common brain gas, reverses autism-like traits in mice. Treating human nerve cells with nitric oxide blocker produced a similar result. In addition, samples from autistic children contained much lower levels of the TSC2 brake protein that blocks nitric oxide.

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This story unfolds in two phases. The iMac G3 signaled Steve Jobs’ comeback. This vibrant all-in-one computer represented a fresh direction in numerous respects. In 1998, Apple eliminated conventional ports and the tangle of cables common to PCs, embracing USB and the then-nascent internet. (Indeed, the “i” in iMac refers to the internet.)

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